前瞻性研究表明先天性感染的發(fā)生率和嚴重性與孕婦受染時間的早晚有關(guān)：妊娠早期感染弓形蟲病的孕婦，如不接受治療則可引起%～%先天性感染而導(dǎo)致自然流產(chǎn)、死胎、早產(chǎn)和新生兒嚴重感染;妊娠中期與后期感染的孕婦分別可引起%～%(其中～%可無癥狀)和～%(內(nèi)%～%可無癥狀)的胎兒感染。受染孕婦如能接受治療，則可使先天性感染的發(fā)生率降低%左右。先天性弓形蟲病的臨床表現(xiàn)不一。多數(shù)嬰兒出生時可無癥狀，其中部分于出生后數(shù)月或數(shù)年發(fā)生視網(wǎng)膜脈絡(luò)膜炎、斜視、失明、癲癇、精神運動或智力遲鈍等。出生時即有癥狀者梋下列不同組合的臨床表現(xiàn)：視網(wǎng)膜脈絡(luò)膜炎;腦積水或小并沒有畸形或無腦兒、顱內(nèi)鈣化，伴脊柱裂、腦脊膜膨出、兔唇腭裂;腎上腺缺如、雙多囊腎;聯(lián)體畸胎等;抽搐、精神運動障礙;淋巴結(jié)腫大、肝脾腫大、發(fā)熱、黃疸、皮疹等。[] 后天獲得性弓形蟲病獲得性弓形蟲病可因蟲體侵襲部位和機體反應(yīng)性而呈現(xiàn)不同的臨床表現(xiàn)。因而無特異癥狀，須與有關(guān)疾病鑒別。患者多數(shù)與職業(yè)、生活方式、飲食習(xí)慣有一定關(guān)系。淋巴結(jié)腫大是獲得性弓形蟲病zui常見的臨床類型，多見于頜下和頸后淋巴結(jié)。其次弓形蟲常累及腦、眼部，引起中樞神經(jīng)系統(tǒng)異常表現(xiàn)，在免疫功能低下者，常表現(xiàn)為腦炎、腦膜腦炎、癲癇和精神異常。
Prospective studies have shown that the incidence and severity of congenital infections are related to the timing of maternal infection: Pregnant women infected with toxoplasmosis in the early stages of pregnancy may cause % to % congenital infections resulting in spontaneous abortions and stillbirths if they are not treated. , Premature birth and serious neonatal infections; pregnant women with mid- and late-term infections can cause fetal infections with %-% (of which ~% can be asymptomatic) and ~% (internal %-% can be asymptomatic). If infected pregnant women can receive treatment, the incidence of congenital infections can be reduced by about %. The clinical manifestations of congenital toxoplasmosis vary. Most babies are asymptomatic at birth, and some of them develop retinochoroiditis, strabismus, blindness, epilepsy, mental activity, or mental retardation several months or years after birth. The clinical manifestations of those with symptoms at birth are the following: retinochoroiditis; no or abnormal brain hydrocephalus, or intracranial calcification, with spina bifida, meningocele, or cleft lip; Such as, double polycystic kidney; conjoined teratogenic; convulsions, mental movement disorders; lymphadenopathy, hepatosplenomegaly, fever, jaundice, rash and so on. [] Acquired toxoplasmosis acquired toxoplasmosis can present with different clinical manifestations due to the site of attack and body reactivity. Therefore, no specific symptoms must be identified with the relevant diseases. Most patients have a certain relationship with occupation, lifestyle, and eating habits. Lymph node enlargement is the most common clinical form of acquired toxoplasmosis and is most commonly found in submandibular and cervical lymph nodes. Second, Toxoplasma gondii often involving the brain, eyes, causing abnormal performance of the central nervous system, in immunocompromised persons, often manifested as encephalitis, meningoencephalitis, epilepsy and mental disorders.

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